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Impact of Arsenic trioxide on the hematological parameters in Rabbit model

Manisha Kumaria* and Anil Kumarb
aDepartment of Zoology, Nirmala College, Ranchi University, Ranchi-834002, Jharkhand
bMDLM Hospital and Research Centre, Ranchi- 835217, Jharkhand
Received : 18th April, 2015; Revised : 22nd May, 2015

Abstract : Arsenic is one of the most dangerous occupational and environmental toxins. Both natural and anthropogenic sources are responsible for the distribution of many toxicants, mainly heavy metals throughout the environment. Arsenic trioxide is a trivalent inorganic compound of arsenic. The animals were divided into three groups. Group I : treated as control. Group II: treated with 0.2mg/kg of As2O3 for 15 days and Group III : treated with 0.6mg/kg of of As2O3 for 7 days. In the arsenic treated groups there was a significant decrease in Hb%, PCV, MCV, MCH, and MCHC content.

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