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Ameliorating effect of Ganoderma lucidum extract against solid Ehrlich Tumor in Swiss Albino Mice

Rekha Kumaria*, Ranjana Kumaria, D. M. Mondheb & Z.A. Wanib
aDepartment of Zoology, A. N. College, Magadh University, Patna, Bihar, India.
bIndian Institute of Integrative Medicines, Jammu- 188001, J & K, India.
Received 25th May, 2013    ;    Revised 20th June, 2013

Abstract : This Paper deals with the reduction of tumor volume by a tiny fungus Ganoderma lucidum. Methanolic extract of G.lucidum was evaluated against solid Ehrlich tumor in male Swiss albino mice. Ix107 EAC cells were injected intramuscularly in right thigh of Swiss male mice .Two treatment group one treated with G. lucidum extract & other with 5 FU along with a Control group were studied. Longest and shortest diameters of tumor were measured with help of vernier calipers. The percent Tumor growth inhibition was calculated on day 13 by comparing the average values of treated groups with that of control group and was found that Ganoderma lucidum extract inhibited tumor growth upto 39.46%.

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