Deokanta* & Nayni Saxenab
aDepartment of Botany, Samastipur College, Samastipur, Bihar, India
bUniversity Department of Zoology, Ranchi University, Ranchi, Jharkhand, India
Received : 13th July, 2022 ; Revised : 14th August, 2022
Abstract– Blood is a good source to measure certain hematological profile which includes Hemoglobin quantity, Total Leucocyte Count (TLC) and Differential Leucocyte Count (DLC) which reflects the alterations of certain biochemical and molecular pathways. Hematological profiles are fluctuating during normal and pathogenesis conditions and can also be correlated with development of carcinogenesis. The mean sample hemoglobin level is 8.93 gm/dL, which is significantly lower (α=0.05) than the control hemoglobin value (14.1 gm/dL). The mean sample TLC level is 23,914 per μL, which is significantly higher (α=0.05) than the control value (8,512 per μL). The mean sample neutrophil level is 20,582 per μL, which is significantly higher (α=0.05) than the control value (6,431 per μL). The mean sample lymphocyte count level is 681 per μL, which is significantly lower (α=0.05) than the control value (1,516 per μL). These alterations may lead to development of carcinogenesis or results due to carcinogenesis and may increase as cancer progresses through successive advanced stages and can be used to establish correlation between extent of alterations and stages of cancer development.
Key words: Total Leucocyte Count, Differential Leucocyte Count, Hemoglobin, Neutrophil, Lymphocyte, Carcinogenesis
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