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Parental Mark – Genome Imprinting

Anshumita Shekhar*
Department of Zoology, K.O. College, Gumla, Ranchi University, Ranchi, Jharkhand, India
Received : 18th February, 2022 ; Revised : 18th March, 2022

Abstract– Genome imprinting is a vital genetic mechanism in mammals and is thought to influence the transfer of nutrients to the foetus and the newborn from the mother versus father. Imprinting defects can involve multilocus or isolated epigametic changes that may have no evident genetic cause or imprinting disruption can be traced back to alteration of cis-acting elements or transacting factors that control the establishment maintenance and erasure of germiline epigametic imprints. The study at transgene methylation has shown that methylation pattern can be in parent origin in specific manner 3′- 7′ suggesting that DNA Methylation may play role in genomic imprinting.

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