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Frequency of ABO blood group and Rh incompatibility among certain population of Bihariganj, Madhepura

Kshamaa*, Pankaj Kumarb & Arun Kumara
aUniversity Department of Zoology, B.N.M. University Madhepura, Bihar, India
bDepartment of Zoology, T. P. College, Madhepura, B.N.M. University Madhepura, Bihar, India
Received : 29th May, 2021 ; Revised : 28th June, 2021

Abstract– In humans, four types of blood groups A, B, AB, and O are present and their inheritance in humans is by the multiple allele method. Recognition of blood group is based on the presence of a special glycoprotein called antigen on the membrane of RBC and also by the absence of antibody in plasma. The person with A blood group has antigen A on the membrane of RBC and antibody B in plasma. Like this, a person with blood group B has antigen B on RBC and antibody A in plasma. In blood group AB, Antigen A and B both are present on the membrane of RBC and there is no kind of antibody present in plasma. There is no kind of antigen present on RBC of people with blood group O. In such people both types of antibodies, A and B are present in blood plasma. The control of inheritance of blood groups is done by gene I which is responsible for the production of antigen. There are three types of allele of gene I. They are IA, IB, and IO. All alleles of gene I are found in persons of all races and ethnicities. Antigen A and B are produced by alleles IA and IB, respectively, while IO does not produce any antibodies.

Key words: ABO blood group, Antibody, Antigen, Rh incompatibility, RBC.

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