Rizwan Ahmad, Prakash Singh & G.B. Chand*
Aquatic Toxicology Laboratory, Department of Zoology, Patna University, Bihar, India
Received : 21st April, 2020 ; Revised : 24th May, 2020
Abstract– Intense anthropogenic activities in terms of non-judicious use of agrochemicals have posed serious threats to the aquatic organism. Fishes being at apex of the aqueous ecosystem get easily victimized to their deleterious impact. In the present study, Clarias batrachus commonly called as “Mangur” has been used as experimental model for assessment of toxic impact of endosulfan on liver and kidney functions. Fishes have been collected from local pond in pre-spawning season having 5″-6″ length and 100-110 gm weight. They were exposed to mild, moderate and high level of endosulfan concentration based on LC50 and impact was assessed after 4, 8 and 12 days through measurement of SGPT, SGOT and Urea level in blood serum. Due to its cyto-biochemical impact on kidney and liver, endosulfan lowers the clearance of urea through the urine and raises its level in blood serum while due to disruption of hepatic tissues, blood serum level of SGPT and SGOT also raised significantly. This study confirms the disruptive effects of endosulfan on kidney and liver functions.