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Effect of Calcium Hypochlorite and Sodium Hypochlorite on the Glomerulus and Bowman’s Capsule of Mice

Joyita Dasa* & Doris D’ Souzab
aP. C. Vigyan College, J.P.University, Chapra, Bihar, India
bPatna Women’s College, Patna University, Patna, Bihar, India
Received : 25th April, 2020 ; Revised : 24th May, 2020

Abstract-The effect of chlorine salts calcium hypochlorites and sodium hypochlorite commonly used for disinfection of water were seen in Swiss albino mice. Mice were given oral doses of 50, 100, 150 and 200 ppm per kg of body weight per day. Significant changes were observed in the glomerulus and Bowman’s capsule after four months treatment with 200 ppm oral dose of both the chemicals. Changes were evident even in lower doses and duration. The decrease in size was significant in both glomerulus and Bowman’s capsule at P <0.05 for the highest dose of 200 ppm and longest duration of four months for both calcium hypochlorite and sodium hypochlorite.

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