Shashi Bhushan Lal* & Moti Lal Gupta
Department of Zoology, B. N. College, Patna University, Patna, Bihar, India
Received : 12th January, 2024 ; Revised : 12th February, 2024
DOI:-https://doi.org/10.5281/zenodo.14263389
Abstract– Catharanthus roseus, a medicinal plant with historical use in diabetes management, has shown potential in reducing oxidative stress and lowering glucose levels in preclinical studies. This study investigates the antidiabetic efficacy of Catharanthus roseus leaf extract in alloxan-induced diabetic mice. Results indicate that Catharanthus roseus extract effectively lowers blood glucose levels and reduces markers of kidney dysfunction, including blood urea, creatinine, SGOT, and SGPT, with effects comparable to rosiglitazone. Thus, Catharanthus roseus has significant rule in therapy for the long-term management of diabetes mellitus, emphasizing its therapeutic benefits and broader applicability in diabetes care. It improve the function of pancreatic tissue by insulin secretion.
Key words: Catharanthus roseus, alloxan, albino mice, Diabetes
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