Tanushreea, Arvind Kumarb & Arun Kumara*
aUniversity Department of Zoology, B. N. Mandal University, Madhepura, Bihar, India.
bDepartment of Zoology, B. N. M. V. College, B. N. Mandal University, Madhepura, Bihar, India.
Received : 20th December, 2023 ; Revised : 20th January, 2024
DOI:-https://doi.org/10.5281/zenodo.14263339
Abstract– The aims of the present study were to assess the mitigating role of Fenugreek extract against gonadotoxicity induced by permethrin on Male Mus musculus. For the research experiment, model animals Mus musculus of the same age group were selected for the research experiment and divided into four experimental variant groups. After the completion of treatment, Sperm counting and Wt. of reproductive organs parameter were included in this research to investigate the mitigating role of Fenugreek extract against gonadotoxicity induced by permethrin. The data obtained from the control and treated group are expressed as mean ± SE and ‘t’ test was used to determine by Excel Software and the level of significance is p < 0.05. The result of sperm count was 175.4 ± 3.5 (C), 90.02 ± 2.8 (PM), 188.6 ± 3.3 (FG) and 133.1 ± 2.2 (PM + FG) and result of reproductive organ wt. of testis – 0.14 ± 1.3 (C), 0.12 ± 0.8 (PM), 0.17 ± 1.0 (FG) and 0.13 ± 1.2 (PM + FG), Seminal vesicles wt. was – 0.41 ± 0.3 (C), 0.36 ± 0.5 (PM), 0.43 ± 0.2 (FG) and 0.39 ± 0.3 (PM + FG) and Vas deferens wt. was 0.21 ± 0.4 (C), 0.17 ± 0.3 (PM), 0.22 ± 0.2 (FG) and 0.23 ± 0.3 (PM + FG) and it is a significant difference to control and treated groups at p< 0.05.
Key words: Gonadoxicity, Mus musculus, Sperm count, Seminal vesicles, Testis, Vas deferens.
