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Heterogeneity and distribution patterns of ABO and RH phenotypes in the Madhepura, Bihar

Rana Pratap Ranjan*, D.N.Singh & Arun Kumar
University Department of Zoology B.N.M.University, Madhepura, Bihar, India
Received : 12th February, 2020 ; Revised : 23rd March, 2020

Abstract: Blood groups (antigens) are proteins, glycoproteins or glycolipids inherited surface markers on the red blood cell membranes, which determine the blood phenotypes of human beings. There are 36 blood group systems with over 300 antigens. Among them, ABO and Rh are of clinical significance. For a safe transfusion, a blood donor and recipient should be ABO and Rh compatible. The heterogeneity of ABO and RhD blood groups systems shows variations in different parts of the world. In Madhepura, there is limited study done on ABO and Rh D blood groups heterogeneity. The aim of this study is to determine the heterogeneity and prevalence of ABO and Rh D blood groups among population of the district. The presence of blood groups was determined by serological techniques both microtitre and tube methods. Commercial monoclonal antisera (anti-A, anti-B, anti-D and Antihuman globulin) were used. The study revealed that there is heterogeneity in the ABO and RhD blood groups.

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