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Impact of water containing high arsenic on the blood metabolites in female mice.

Kumari Soni*& Arun Kumar
University Department of Zoology, B.N.Mandal University, Madhepura, Bihar, India
Received : 18th October 2018; Revised : 5th January 2019

Abstract : Arsenic is a naturally occurring toxic metalloid. Levels of naturally occurring arsenic in groundwater above the drinking water standard of 10 ìg /L are not uncommon. Inorganic arsenic (iAs) is a complete transplacental carcinogen in mice. Previous studies have demonstrated that in utero exposure to inorganic arsenic promotes cancer in adult mouse offspring, possibly acting through epigenetic mechanisms. Humans and rodents have the ability to convert arsenic to its methylated metabolites. Arsenic, from both natural and anthropogenic sources, is mainly transported in the environment by water. The form and concentration of arsenic depends on several factors, including whether the water is oxygenated, the degree of biological activity, the type of water source and the proximity of the water source to arsenic-rich geological formations and other anthropogenic sources.

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