Jayaram kumar K.*, Panpalia S. G.,Santosh Kumar G.
Department of Pharmaceutical Sciences and Technology, Birla Institute of Technology,
Mesra, Ranchi, Jharkhand, India.
Abstract : Starch was isolated from seeds ofCucumis melo. L and further carboxymethylated starches was prepared by using monochloro acetic acid. The granules were prepared by wet granulation method by using different concentrations of native and carboxymethylation. The micrometric properties of the granules like bulk density, tapped density, Hausner ratio, Carr’s index and angle repose were determined. The micrometric properties revealed that compressibility and flowability of granules improved after carboxymethylation, suggesting its use in formulation of tablets