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Lamina propria macrophages of intestine of Guinea Pig

Veena Kumari & Arun Kumar*
University Department of Zoology, B.N.M University, Madhepura, Bihar, India
Received : 17th April, 2017; Revised : 07th June, 2017

Abstract : The macrophages of lamina propria were commonly found both in the small and the large intestine of guinea pigs, mice, rats, and in human duodenum. The frequency of macrophage occurrence was highest in the lamina propria of villous apices of the small intestine and beneath the lining epithelium of the large intestine. In the cytoplasm of lamina propria macrophages localized in those regions. Feulgen-positive (DNA-containing) granules could be observed particularly in the guinea pig intestine. Lamina propria containing the highest accumulation of macrophages i.e. at the apices of villi of the small intestine and beneath the lining epithelium of the large intestine. Labeled nuclei of macrophages were observed scarcely and much less frequently than were labeled cytoplasmic granules. It is suggested that the lamina propria macrophages may play a role in the phagocytosis of some migrating cells of the intestinal mucosa, most probably of the sheath-fibroblasts and/or intraepi-thelial lymphocytes.

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