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Alteration in white blood cells after cypermethrin and cyhalothrin toxicity in albino rats

Padma Saxena
Department of Zoology, D.A.V. College, Kanpur.
Received , 5th December, 2014; Revised: 7th January, 2015

Abstract : Pesticides have been widely used to control pest and pest-related diseases in agriculture, fishery, forestry and the food industry. The aim of this study was to assess the effect of cypermethrin and cyhalothrin in the albino rats. The effect was based on results of acute (1 day) & sub-chronic (7, 14, 21 days) toxicity tests and on a comparison of results of hematological examination of a control and an experimental group exposed to cypermethrin and cyhalothrin. The experimental groups of the albino rats showed significantly higher values (p < 0.05) of total leukocyte and neutrophils count while lymphocytes count showed significantly lower values (p < 0.05) after acute and sub-chronic treatments compared to the control group. Changes in the values of the leucocyte profile after exposure of cypermethrin and cyhalothrin may be referred to disruption of haematopoiesis in the albino rats can serve as an indicator for similar effects on other allied and higher mammalian species.

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