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Circadian rhythmicity in the head kidney and spleen cells in snakehead teleost, Channa punctatus

Sheena Farheen Khan, Sushant Kumar Verma & Manish Kumar Tripathi*
Department of Zoology, School of Studies of Life Science, Guru Ghasidas Vishwavidyalaya, Bilaspur, Chhattisgarh, India

Received : 11th October, 2024 ; Revised : 10th November, 2024
DOI:-https://doi.org/10.5281/zenodo.15733985

Abstract– The endogenously occurring circadian rhythm functions as an important signaling mechanism in animals to maintain physiological homeostasis in respect with cyclic environmental variations. Cellularity is one of the most important components in animal’s physiology that provides information about overall health of the organism. This study was designed to evaluate the circadian rhythmicity in the cellularity of fish lymphoid organs, head kidney and spleen in the freshwater snakehead teleost, Channa punctatus. The fish were sacrificed multiple times with equal time interval during 24-h and head kidney and splenic cellularity was calculated. To analyze the circadian rhythm in the cellularity, cosinor rhythmometry analysis was performed. The significant 24-h variation was observed with elevation in the cellularity during the dark phase of the day in both head kidney and spleen. Additionally, results from cosinor rhythmometry observed significant circadian rhythm in cellularity of the lymphoid organs. These findings contribute to broader understandings of chronobiology in aquatic organisms emphasizing the importance of circadian regulation in immune homeostasis.

Keywords: Circadian rhythm, Cellularity, Fish, Cosinor analysis, Channa punctatus

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