Arvind Kumara* & Vinay Bhushan Kumarb
aDepartment of Botany, Patliputra University, Patna, Bihar, India
bDepartment of Botany, T.P.S. College, Patliputra University, Patna, Bihar, India
Received : 18th June, 2024 ; Revised : 16th July, 2024
DOI:-https://doi.org/10.5281/zenodo.15106364
Abstract– Medicinal plants are rich in pharmacologically active compounds, and Cissus quadrangularis L., a species from the Vitaceae family, is widely recognized for its therapeutic properties. Known for its succulent stems, this plant is capable of producing various bioactive molecules. The aim of this study was to evaluate the antibacterial activity of Cissus quadrangularis L. stem extract, prepared using different solvents, against selected plant pathogens. The antibacterial activity was assessed using the disc diffusion method, while the Minimum Inhibitory Concentration (MIC) was determined through the broth dilution method. The results showed that the dichloromethane extract exhibited the strongest antibacterial effect against Xanthomonas campestris (ZOI: 11.84±0.15) and Ralstonia solanacearum (ZOI: 12.28±0.12), whereas the hexane and acetone extracts demonstrated the weakest activity against Xanthomonas campestris (ZOI: 1.75±0.17) and Ralstonia solanacearum (ZOI: 6.45±0.15), respectively. In terms of MIC, the hexane extract showed the highest values against Xanthomonas campestris (MIC – 75 μg & IC50 – 46.77 μg), while the dichloromethane extract had the lowest (MIC – 40 μg & IC50 – 31.59 μg). For Ralstonia solanacearum, the acetone extract displayed the highest MIC values (MIC – 60 μg & IC50 – 38.63 μg), while the dichloromethane extract showed the lowest (MIC – 40 μg & IC50 – 31.04 μg). The positive results from this study support the traditional use of Cissus quadrangularis as an antibacterial agent against the tested plant pathogens.
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