Synthesis of some 5-(4-substituted aryl)-4, 5-dihydro-3-(naphtha [2,1-b] furan-2-yl) isoxazole as potential antimicrobial agents

Dhanaji V. Jadhav*
Y. C. Art and Science College, Mangrulpir. 444403 (INDIA)
Received : 11th July, 2015; Revised : 22nd August, 2015

Abstract : A series of new arylisoxazole derivative were prepared by cyclocondentation route of various substituted chalcones in presence of alcoholic solution of potassium hydroxide at reflux temperature. A synthesized isoxazolinewere characterized by means of their IR, 1H NMRdata and elemental analysis. The synthesized isoxazoline derivatives were evaluated for antimicrobial and antifungal activities, some of them were found to possess significant activity.

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