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Platelet Physiology and Pharmacology : Expectations and Limitations

Gundu H.R. Rao*
Lillehei Heart Institute, University of Minnesota, Minneapolis, Minnesota USA

Received 19th March, 2009; Revised 7th Sept 2009

 Abstract : In South Asian countries, the incidence of coronary heart disease and the type-2 diabetes are comparatively higher. The author has explained the role of platelet physiology and antiplatelet therapy. Possibly platelet inhibition specially of vWF (von Willebrand Factor) interaction with GPlb platelet receptor is an important mechanism in the management of acute stroke.

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